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Welcome


ChenLab, Precision Nutrition and Metabolism Innovation Team, Huazhong Agricultural University, was established in September 2016 by Zhen-Xia Chen, Professor at Huazhong Agricultural University.

Our research focus on:
Using the ‘Drosophila-vertebrate-human’ comparative genomics research strategy, through the integration and analysis of multi-omics data on animal and human nutritional health, we will assess the effects of ‘gene-sex-nutrition’ interactions on the body and their molecular mechanisms, with the aim of providing the nation with a personalised dietary and nutritional programme. The aim is to provide the nation with personalised dietary and nutritional programmes to treat the future.

The main research interests include:
Food nutritional health utility mining.

Animal phenomics technology development.

Functional and evolutionary studies of non-coding structural elements.

News


  • 2023-10-30: "EndoQuad: a comprehensive genome-wide experimentally validated endogenous G-quadruplex database." has been accepted by Nucleic Acids Research. Online

  • 2023-07-03: "Male-Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development." has been accepted by Advanced Science. Online

  • 2023-06-28: "In vivo dynamics and regulation of DNA G-quadruplex structures in mammals." has been accepted by Cell & Bioscience. Online

  • 2023-05-25: "Integrating massive RNA-seq data to elucidate transcriptome dynamics in Drosophila melanogaster." has been accepted by Briefings in Bioinformatics. Online

  • 2022-11-21: "Gut microbiome in tumorigenesis and therapy of colorectal cancer." has been accepted by Journal of Cellular Physiology. Online

  • 2022-08-27: "Dynamic Spatial-Temporal Expression Ratio of X Chromosome to Autosomes But Stable Dosage Compensation in Mammals." has been accepted by Briefings in Bioinformatics. Online